ES8206484A1 - Un procedimiento para preparar derivados de tetrahidroiso- quinoleinas - Google Patents
Un procedimiento para preparar derivados de tetrahidroiso- quinoleinasInfo
- Publication number
- ES8206484A1 ES8206484A1 ES506302A ES506302A ES8206484A1 ES 8206484 A1 ES8206484 A1 ES 8206484A1 ES 506302 A ES506302 A ES 506302A ES 506302 A ES506302 A ES 506302A ES 8206484 A1 ES8206484 A1 ES 8206484A1
- Authority
- ES
- Spain
- Prior art keywords
- hydroxy
- tetrahydroisoquinolines
- hydrogen
- carbon atoms
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000002887 hydroxy group Chemical group [H]O* 0.000 title abstract 3
- 239000002243 precursor Substances 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 230000000202 analgesic effect Effects 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- UWYZHKAOTLEWKK-UHFFFAOYSA-N 1,2,3,4-tetrahydroisoquinoline Chemical class C1=CC=C2CNCCC2=C1 UWYZHKAOTLEWKK-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 150000003526 tetrahydroisoquinolines Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19822780A | 1980-10-17 | 1980-10-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES506302A0 ES506302A0 (es) | 1982-08-16 |
| ES8206484A1 true ES8206484A1 (es) | 1982-08-16 |
Family
ID=22732515
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES506302A Expired ES8206484A1 (es) | 1980-10-17 | 1981-10-16 | Un procedimiento para preparar derivados de tetrahidroiso- quinoleinas |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0051190A3 (en]) |
| KR (1) | KR830007568A (en]) |
| ES (1) | ES8206484A1 (en]) |
| GR (1) | GR75354B (en]) |
| IL (1) | IL63918A0 (en]) |
| PT (1) | PT73785B (en]) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3308554A1 (de) * | 1983-03-10 | 1984-09-13 | Hoechst Ag, 6230 Frankfurt | 1-/1,3-dioxolan-2-ylmethyl)-azole, ihre salze, verfahren zu ihrer herstellung und ihre verwendung |
| AU679765B2 (en) * | 1993-06-22 | 1997-07-10 | Abbott Gmbh & Co. Kg | Isoquinoline derivatives as therapeutic agents |
| GB9708805D0 (en) | 1997-05-01 | 1997-06-25 | Smithkline Beecham Plc | Compounds |
| GB9810876D0 (en) | 1998-05-20 | 1998-07-22 | Smithkline Beecham Plc | Compounds |
| PL347237A1 (en) | 1998-10-08 | 2002-03-25 | Smithkline Beecham Plc | Tetrahydrobenzazepine derivatives useful as modulators of dopamine d3 receptors (antipsychotic agents) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR868733A (fr) * | 1939-10-14 | 1942-01-14 | Troponwerke Dinklage & Co | Procédé pour la fabrication des composés d'isoquinoleine |
| GB1183349A (en) * | 1967-11-30 | 1970-03-04 | Roche Products Ltd | Novel Isoquinoline Derivatives and the Manufacture Thereof |
| FR7607M (en]) * | 1968-04-25 | 1970-01-19 | ||
| FR2054483A1 (en) * | 1969-07-11 | 1971-04-23 | Anvar | Sympatholytic tsoquinoline derivs |
| FR2059980A1 (en) * | 1969-08-21 | 1971-06-11 | Roussel Uclaf | N-(2-phenylethyl) tetrahydroiso quinolines |
| FR2059979A1 (en) * | 1969-08-21 | 1971-06-11 | Roussel Uclaf | Subst n-benzyl tetrahydroisoquinolinesantiin |
-
1981
- 1981-09-23 IL IL63918A patent/IL63918A0/xx unknown
- 1981-09-29 GR GR66149A patent/GR75354B/el unknown
- 1981-10-07 PT PT73785A patent/PT73785B/pt unknown
- 1981-10-16 ES ES506302A patent/ES8206484A1/es not_active Expired
- 1981-10-16 EP EP81108418A patent/EP0051190A3/en not_active Withdrawn
- 1981-10-17 KR KR1019810003956A patent/KR830007568A/ko not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| PT73785A (en) | 1981-11-01 |
| IL63918A0 (en) | 1981-12-31 |
| ES506302A0 (es) | 1982-08-16 |
| KR830007568A (ko) | 1983-10-21 |
| EP0051190A3 (en) | 1982-06-23 |
| EP0051190A2 (en) | 1982-05-12 |
| PT73785B (en) | 1983-01-17 |
| GR75354B (en]) | 1984-07-13 |
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